Endocrine Abstracts

Anacardium occidentale is a multi-purpose tree of the anacardae family with great economic and medicinal value. The leaf of the tree has been reported to possess hypoglycaemic and anti-diabetic properties. However, literature is devoid of any molecular basis for the potent effects observed. This study evaluated the molecular mechanisms underlying the efficacy and safety of the leaves by investigating glucagon-like peptide 1, insulin and kidney injury molecule genes us...

Anacardium occidentale (cashew tree) belongs to the Anacardiaceae family and has been well used in folklore medicine for the treatment of various ailments such as gastrointestinal disorders, hypertension and diabetes. Literature is replete with reported anti-diabetic actions of cashew leaf. The molecular mechanism of the hypoglycemic activity of A. occidentale was investigated in this study. Insulin, Glucagon like peptide-1 (GLP-1), dipeptidyl peptidase-4 (DP...